148 lines
14 KiB
XML
148 lines
14 KiB
XML
<document id="AD979818FABBACAD8A18A5B599AB4954" ID-CLB-Dataset="264564" ID-DOI="10.1016/j.phytochem.2019.112222" ID-GBIF-Dataset="4a860314-bd9c-4c55-9f10-852e402b1aef" ID-ISSN="1873-3700" ID-Zenodo-Dep="8292998" IM.illustrations_approvedBy="carolina" IM.materialsCitations_approvedBy="felipe" IM.metadata_approvedBy="felipe" IM.taxonomicNames_approvedBy="carolina" IM.treatments_approvedBy="carolina" checkinTime="1693250931468" checkinUser="felipe" docAuthor="Micucci, M., Bolchi, C., Budriesi, R., Cevenini, M., Maroni, L., Capozza, S., Chiarini, A., Pallavicini, M. & Angeletti, A." docDate="2020" docId="03E4D873FFF0DC50FFDBB0D7BC601D78" docLanguage="en" docName="Phytochemistry.170.112222.pdf" docOrigin="Phytochemistry (112222) 170" docSource="http://dx.doi.org/10.1016/j.phytochem.2019.112222" docStyle="DocumentStyle:F36D69FC8B198FBE91029DF9C24697D3.5:Phytochemistry.2020-.journal_article" docStyleId="F36D69FC8B198FBE91029DF9C24697D3" docStyleName="Phytochemistry.2020-.journal_article" docStyleVersion="5" docTitle="Aniba canelilla Mez" docType="treatment" docVersion="4" lastPageNumber="8" masterDocId="FFDDA00BFFF7DC57FFBFB12FBD10184C" masterDocTitle="Antihypertensive phytocomplexes of proven efficacy and well-established use: Mode of action and individual characterization of the active constituents" masterLastPageNumber="19" masterPageNumber="1" pageNumber="8" updateTime="1693417694953" updateUser="ExternalLinkService">
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<mods:title id="E18C17E76A4639C7F3269EE195103065">Antihypertensive phytocomplexes of proven efficacy and well-established use: Mode of action and individual characterization of the active constituents</mods:title>
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<mods:namePart id="B03D1F5EED23248902508138994C4ACE">Micucci, M.</mods:namePart>
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<mods:affiliation id="DC85414BBC98EC60D09C9F3AB3897F4A">∗ & Department of Pharmacy and Biotechnology, Alma Mater Studiorum University of Bologna, Via Belmeloro, 6, 40126, Italy</mods:affiliation>
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<mods:namePart id="32D44BC7AA0C6611EF775B8322801930">Bolchi, C.</mods:namePart>
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<mods:namePart id="E6C436F62E989D42FFB3AE8EC67840B2">Budriesi, R.</mods:namePart>
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<mods:namePart id="8C3581A31B05AE4B23B59633382A0AF3">Cevenini, M.</mods:namePart>
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<mods:namePart id="D5DC265914B51F883C8674F6928C9FF4">Capozza, S.</mods:namePart>
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<mods:title id="A01F5E84420DD95EF5D43EBC222A06D7">Phytochemistry</mods:title>
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<mods:date id="88F31011EBA62468B18D55BDBF3E615C">2020</mods:date>
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<treatment id="03E4D873FFF0DC50FFDBB0D7BC601D78" ID-DOI="http://doi.org/10.5281/zenodo.8302642" ID-Zenodo-Dep="8302642" LSID="urn:lsid:plazi:treatment:03E4D873FFF0DC50FFDBB0D7BC601D78" httpUri="http://treatment.plazi.org/id/03E4D873FFF0DC50FFDBB0D7BC601D78" lastPageNumber="8" pageId="7" pageNumber="8">
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<subSubSection id="C3573AEEFFF0DC50FFDBB0D7BC841A47" box="[100,404,504,523]" pageId="7" pageNumber="8" type="nomenclature">
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<paragraph id="8BF26965FFF0DC50FFDBB0D7BC841A47" blockId="7.[100,404,504,523]" box="[100,404,504,523]" pageId="7" pageNumber="8">
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<heading id="D0BADE09FFF0DC50FFDBB0D7BC841A47" bold="true" box="[100,404,504,523]" fontSize="36" level="1" pageId="7" pageNumber="8" reason="1">
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<emphasis id="B939B577FFF0DC50FFDBB0D7BC841A47" bold="true" box="[100,404,504,523]" italics="true" pageId="7" pageNumber="8">
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2.8.
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<taxonomicName id="4C4D12E6FFF0DC50FF2DB0D7BC841A47" ID-CoL="672CN" ID-ENA="2803977" authority="(Kunth) Mez" authorityName="Mez" baseAuthorityName="Kunth" box="[146,404,504,523]" class="Magnoliopsida" family="Lauraceae" genus="Aniba" kingdom="Plantae" order="Laurales" pageId="7" pageNumber="8" phylum="Tracheophyta" rank="species" species="canelilla">Aniba canelilla (Kunth) Mez</taxonomicName>
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</emphasis>
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</heading>
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</paragraph>
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<subSubSection id="C3573AEEFFF0DC50FF3AB300BC601D78" pageId="7" pageNumber="8" type="description">
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<paragraph id="8BF26965FFF0DC50FF3AB300BDCF1B6E" blockId="7.[100,771,559,1332]" pageId="7" pageNumber="8">
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<taxonomicName id="4C4D12E6FFF0DC50FF3AB300BC981A0E" authority="(Kunth) Mez" authorityName="Mez" baseAuthorityName="Kunth" box="[133,392,559,578]" class="Magnoliopsida" family="Lauraceae" genus="Aniba" kingdom="Plantae" order="Laurales" pageId="7" pageNumber="8" phylum="Tracheophyta" rank="species" species="canelilla">
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<emphasis id="B939B577FFF0DC50FF3AB300BC1B1A0E" bold="true" box="[133,267,559,578]" italics="true" pageId="7" pageNumber="8">Aniba canelilla</emphasis>
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(Kunth) Mez
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</taxonomicName>
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(
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<taxonomicName id="4C4D12E6FFF0DC50FE2AB300BCE71A0E" box="[405,503,559,578]" class="Magnoliopsida" family="Lauraceae" kingdom="Plantae" order="Laurales" pageId="7" pageNumber="8" phylum="Tracheophyta" rank="family">Lauraceae</taxonomicName>
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) [Syn.
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<taxonomicName id="4C4D12E6FFF0DC50FD84B300BFB41A0E" box="[571,676,559,578]" class="Magnoliopsida" family="Lauraceae" genus="Aniba" kingdom="Plantae" order="Laurales" pageId="7" pageNumber="8" phylum="Tracheophyta" rank="species" species="elliptica">A. Elliptica</taxonomicName>
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A.C. SM.,
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<taxonomicName id="4C4D12E6FFF0DC50FFDBB364BC601A12" authority="Kunth" authorityName="Kunth" box="[100,368,587,606]" class="Magnoliopsida" family="Lauraceae" genus="Cryptocarya" kingdom="Plantae" order="Laurales" pageId="7" pageNumber="8" phylum="Tracheophyta" rank="species" species="canelilla">Cryptocarya canelilla Kunth</taxonomicName>
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], also known as ‘‘casca-preciosa’‘, is a plant belonging to
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<taxonomicName id="4C4D12E6FFF0DC50FF5CB348BC521A36" box="[227,322,615,634]" class="Magnoliopsida" family="Lauraceae" kingdom="Plantae" order="Laurales" pageId="7" pageNumber="8" phylum="Tracheophyta" rank="family">Lauraceae</taxonomicName>
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family, growing in the Amazon region. In folk medicine, the bark is used to prepare decoctions that are believed to exert antispasmodic, digestive stimulating, and carminative properties. Chemical composition of
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<taxonomicName id="4C4D12E6FFF0DC50FEE5B394BCD01A82" box="[346,448,699,718]" class="Magnoliopsida" family="Lauraceae" genus="Cryptocarya" kingdom="Plantae" order="Laurales" pageId="7" pageNumber="8" phylum="Tracheophyta" rank="species" species="canelilla">
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<emphasis id="B939B577FFF0DC50FEE5B394BCD01A82" bold="true" box="[346,448,699,718]" italics="true" pageId="7" pageNumber="8">A. canelilla</emphasis>
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</taxonomicName>
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wood and bark oil includes benzenoids and terpenoids, 1-nitro-2-phenylethane and methyleugenol being the two major components (
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<figureCitation id="137675E0FFF0DC50FE11B3DCBCF51B4A" box="[430,485,755,774]" captionStart="Fig" captionStartId="7.[100,130,1940,1957]" captionTargetBox="[106,764,1761,1918]" captionText="Fig. 8. The main antihypertensive constituents of Aniba canelilla (Kunth) Mez essential essential oil." figureDoi="http://doi.org/10.5281/zenodo.8302628" httpUri="https://zenodo.org/record/8302628/files/figure.png" pageId="7" pageNumber="8">Fig. 8</figureCitation>
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) (Giongo et al., 2017; Lahlou et al., 2005).
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</paragraph>
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<paragraph id="8BF26965FFF0DC50FF3AB204BFDE1CB0" blockId="7.[100,771,559,1332]" pageId="7" pageNumber="8">
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The essential oil causes a concentration-dependent reduction of potassium-induced contraction of rat aorta with endothelium and it counters CaCl
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<subScript id="17C96B20FFF0DC50FF59B244BDFF1B34" attach="left" box="[230,239,875,888]" fontSize="5" pageId="7" pageNumber="8">2</subScript>
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-induced contractions, but not those induced by caffeine suggesting an inhibition of calcium inward current (Lahlou et al., 2005). In conscious rats pretreated with L-NAME, the hypotensive effect of the essential oil was partly, but significantly reduced supporting the essential oil ability to affect the endothelial L-arginine/nitric oxide pathway (Lahlou et al., 2005). These effects are mainly due to 1-nitro-2- phenylethane (
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<figureCitation id="137675E0FFF0DC50FF4CB525BC391C51" box="[243,297,1034,1053]" captionStart="Fig" captionStartId="7.[100,130,1940,1957]" captionTargetBox="[106,764,1761,1918]" captionText="Fig. 8. The main antihypertensive constituents of Aniba canelilla (Kunth) Mez essential essential oil." figureDoi="http://doi.org/10.5281/zenodo.8302628" httpUri="https://zenodo.org/record/8302628/files/figure.png" pageId="7" pageNumber="8">Fig. 8</figureCitation>
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), that was shown to induce vasorelaxant and hypotensive effects
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<emphasis id="B939B577FFF0DC50FEB7B509BC261C75" bold="true" box="[264,310,1062,1081]" italics="true" pageId="7" pageNumber="8">in vit</emphasis>
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ro and
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<emphasis id="B939B577FFF0DC50FEC4B509BCA71C75" bold="true" box="[379,439,1062,1081]" italics="true" pageId="7" pageNumber="8">in vivo</emphasis>
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through a myogenic endothelium-independent mechanism (de Siqueira et al., 2010; Interaminense Lde et al., 2011; Interaminense Lde et al., 2013). The other main constituent, methyleugenol (
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<figureCitation id="137675E0FFF0DC50FEEEB556BC971CC0" box="[337,391,1145,1164]" captionStart="Fig" captionStartId="7.[100,130,1940,1957]" captionTargetBox="[106,764,1761,1918]" captionText="Fig. 8. The main antihypertensive constituents of Aniba canelilla (Kunth) Mez essential essential oil." figureDoi="http://doi.org/10.5281/zenodo.8302628" httpUri="https://zenodo.org/record/8302628/files/figure.png" pageId="7" pageNumber="8">Fig. 8</figureCitation>
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), was also studied for its cardiovascular effects. In particular, it was found to elicit hypotension in either anaesthetized or conscious rats through an active vascular relaxation, significantly reduced by pretreatment with L- NAME or mechanical endothelium removal (Lahlou et al., 2004; Magalhaes et al., 2008).
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</paragraph>
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<paragraph id="8BF26965FFF0DC50FF3AB42ABC601D78" blockId="7.[100,771,559,1332]" pageId="7" pageNumber="8">
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Ethanol extract of
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<taxonomicName id="4C4D12E6FFF0DC50FE88B42ABC8C1D54" box="[311,412,1285,1304]" class="Magnoliopsida" family="Lauraceae" genus="Cryptocarya" kingdom="Plantae" order="Laurales" pageId="7" pageNumber="8" phylum="Tracheophyta" rank="species" species="canelilla">
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<emphasis id="B939B577FFF0DC50FE88B42ABC8C1D54" bold="true" box="[311,412,1285,1304]" italics="true" pageId="7" pageNumber="8">A. canelilla</emphasis>
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</taxonomicName>
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is also endowed of antioxidant properties (Martins et al., 2016).
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</paragraph>
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</subSubSection>
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</treatment>
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</document> |