137 lines
14 KiB
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137 lines
14 KiB
XML
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<mods:title id="37029B9E54065887BC9577A6AF0CED87">Eupholides A H, abietane diterpenoids from the roots of Euphorbia fischeriana, and their bioactivities</mods:title>
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<mods:namePart id="0E98F89F665D2E401E828F9C42E5C825">Li, Da-Wei</mods:namePart>
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<mods:namePart id="82FEDB83A9B71B0ACAA25BD7EDDDA9C0">Ma, Yu-Fang</mods:namePart>
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<treatment id="03F57F05FFEDFF900A27822AFE83FCAF" LSID="urn:lsid:plazi:treatment:03F57F05FFEDFF900A27822AFE83FCAF" httpUri="http://treatment.plazi.org/id/03F57F05FFEDFF900A27822AFE83FCAF" lastPageNumber="5" pageId="4" pageNumber="5">
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<emphasis id="B9281201FFEDFF900A27822AFD2AFDE3" bold="true" box="[100,753,593,613]" italics="true" pageId="4" pageNumber="5">
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2.2. Inhibitory effects of compounds 1–15 on
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<taxonomicName id="4C5CB590FFEDFF900BBE822AFD2AFDE3" ID-CoL="44W74" ID-ENA="1310115" authority="(Zopf, 1883) Lehmann & Neumann, 1896" authorityName="(Zopf, 1883) Lehmann & Neumann" box="[509,753,594,613]" class="Actinobacteridae" family="Mycobacteriaceae" genus="Mycobacterium" kingdom="Bacteria" order="Actinomycetales" pageId="4" pageNumber="5" phylum="Actinobacteria" rank="species" species="tuberculosis">Mycobacterium tuberculosis</taxonomicName>
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</emphasis>
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The inhibitory effect of isolated diterpenoids against
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<taxonomicName id="4C5CB590FFEDFF90083882F2FCDAFD1A" authority="(Zopf, 1883) Lehmann & Neumann, 1896" box="[635,769,649,669]" class="Actinobacteridae" family="Mycobacteriaceae" genus="Mycobacterium" kingdom="Bacteria" order="Actinomycetales" pageId="4" pageNumber="5" phylum="Actinobacteria" rank="species" species="tuberculosis">
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<emphasis id="B9281201FFEDFF90083882F2FCDAFD1A" bold="true" box="[635,769,649,669]" italics="true" pageId="4" pageNumber="5">M. tuberculosis</emphasis>
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H37Ra was evaluated using resazurin as the staining reagent. As a result, no
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<taxonomicName id="4C5CB590FFEDFF900AC082BAFED1FD52" authority="(Zopf, 1883) Lehmann & Neumann, 1896" box="[131,266,705,725]" class="Actinobacteridae" family="Mycobacteriaceae" genus="Mycobacterium" kingdom="Bacteria" order="Actinomycetales" pageId="4" pageNumber="5" phylum="Actinobacteria" rank="species" species="tuberculosis">
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<emphasis id="B9281201FFEDFF900AC082BAFED1FD52" bold="true" box="[131,266,705,725]" italics="true" pageId="4" pageNumber="5">M. tuberculosis</emphasis>
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bacterial cells were observed for co-incubation with compounds
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<emphasis id="B9281201FFEDFF900A9582A5FF22FD76" bold="true" box="[214,249,733,753]" pageId="4" pageNumber="5">6–8</emphasis>
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at 50 μM, which indicated their MIC values. The other diterpenoids could not thoroughly inhibit the proliferation of
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<taxonomicName id="4C5CB590FFEDFF900A27836EFF31FCAE" authority="(Zopf, 1883) Lehmann & Neumann, 1896" box="[100,234,789,809]" class="Actinobacteridae" family="Mycobacteriaceae" genus="Mycobacterium" kingdom="Bacteria" order="Actinomycetales" pageId="4" pageNumber="5" phylum="Actinobacteria" rank="species" species="tuberculosis">
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<emphasis id="B9281201FFEDFF900A27836EFF31FCAE" bold="true" box="[100,234,789,809]" italics="true" pageId="4" pageNumber="5">M. tuberculosis</emphasis>
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at 100 μM.
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</treatment>
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