Phytochemistry of the genus Skimmia (Rutaceae) Author Epifano, Francesco Dipartimento di Farmacia, Università ‘‘ G. D’Annunzio’ ’ Chieti-Pescara, Via dei Vestini 31, 66013 Chieti Scalo, CH, Italy Author Fiorito, Serena Author Genovese, Salvatore Author Granica, Sebastian Author Vitalini, Sara Author Zidorn, Christian text Phytochemistry 2015 2015-07-31 115 1 27 43 http://dx.doi.org/10.1016/j.phytochem.2015.02.014 journal article 285349 10.1016/j.phytochem.2015.02.014 d30e1c4c-6a0f-4e42-97ec-8f9abb4e26ea 1873-3700 10486867 3.1. S. anquetilia S. anquetilia is an aromatic erect or creeping shrub, native to the Himalayan region and often cultivated for decorative purposes ( Kumar et al., 2012 ). An ethanolic extract of leaves from S. anquetilia yielded six coumarins, 7,8-dihdroxy-6-[3 0 -β- D- glucopyranosyloxy-2 0 (Ę)-hydroxy-3 0 -methylbutyl]-coumarin glucoside 34 , 6- (2,3-dihydroxy-3-methylbutyl)-7-methoxycoumarin 30 , skimmine 22 , osthol 38 , esculetin 23 , and scopoletin 24 . Moreover, the coumarin 6-methoxy-7-(2 0 -hydroxy-3 0 -methylbutyl)-coumarin 33 was isolated (Sharma et al., 2008). Prakash et al. (2011) showed that essential oils separately obtained by hydro-distillation from seeds and fruits and analysed by GC–MS contained up to 70 compounds. Fatty acids and their esters were found to be common components for both in similar percentages. On the other hand α- cadinol, α- terpineol, selinene, neo-isolongifolene, linalool, cis -Z-α- bisabolene oxide, aromadendrene, and ( ― )-selinene were the main points of differences between the two essential oils. The essential oil obtained from flowers and leaves and analysed by the same methodology as above indicated the presence of β- phellandrene (1.8% in leaves and 18.4% in flowers), geijerene (2.0%, 15.0%), germacrene B (11.6%, 2.0%), linalyl acetate (7.3%, 11.2%), linalool (9.5%, 9.4%), αterpineol (5.6%, 4.4%), and pregeijerene (0.2%, 5.6%) as the most abundant mono- and sesquiterpenes (Gondwal et al., 2012).