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<document id="4880900AD6228988B01F130B322E8213" ID-CLB-Dataset="285349" ID-DOI="10.1016/j.phytochem.2015.02.014" ID-GBIF-Dataset="d30e1c4c-6a0f-4e42-97ec-8f9abb4e26ea" ID-ISSN="1873-3700" ID-Zenodo-Dep="10486867" IM.bibliography_approvedBy="guilherme" IM.illustrations_approvedBy="guilherme" IM.materialsCitations_approvedBy="felipe" IM.metadata_approvedBy="felipe" IM.tables_approvedBy="guilherme" IM.taxonomicNames_approvedBy="guilherme" IM.treatments_approvedBy="jonas" checkinTime="1704950218509" checkinUser="felipe" docAuthor="Epifano, Francesco, Fiorito, Serena, Genovese, Salvatore, Granica, Sebastian, Vitalini, Sara & Zidorn, Christian" docDate="2015" docId="03A0E701A375FFB5FCDA048EFA3740F4" docLanguage="en" docName="Phytochemistry.115.27-43.pdf" docOrigin="Phytochemistry 115 (1)" docSource="http://dx.doi.org/10.1016/j.phytochem.2015.02.014" docStyle="DocumentStyle:9E596C34F4E94307D29315B03ACE1007.6:Phytochemistry.2014-2019.journal_article" docStyleId="9E596C34F4E94307D29315B03ACE1007" docStyleName="Phytochemistry.2014-2019.journal_article" docStyleVersion="6" docTitle="Skimmia repens Nakai" docType="treatment" docVersion="6" lastPageNumber="35" masterDocId="FF999F79A37DFFBDFFE50019FFF4462D" masterDocTitle="Phytochemistry of the genus Skimmia (Rutaceae)" masterLastPageNumber="43" masterPageNumber="27" pageNumber="35" updateTime="1705416209838" updateUser="jonas">
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<mods:titleInfo id="FA02DE76337509C43C317968EB31F8D7">
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<mods:title id="6B9DAEECA61E08FAC3495D5C40A657E9">Phytochemistry of the genus Skimmia (Rutaceae)</mods:title>
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<mods:namePart id="1989BFE6888C6AFE98DEEE03D957F279">Epifano, Francesco</mods:namePart>
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<mods:affiliation id="DCE060241AE4E402B2B13C4BE674B691">Dipartimento di Farmacia, Università ‘‘ G. D’Annunzio’ ’ Chieti-Pescara, Via dei Vestini 31, 66013 Chieti Scalo, CH, Italy</mods:affiliation>
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</mods:role>
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<mods:namePart id="CB1BF78DE526030C4F150B6EB2C7544C">Fiorito, Serena</mods:namePart>
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</mods:name>
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<mods:name id="AF02741A0BAC9C9D0C98E50C43956417" type="personal">
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</mods:role>
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<mods:namePart id="16939BE0136111A4A3000EFD9239B855">Genovese, Salvatore</mods:namePart>
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</mods:name>
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<mods:name id="814129EF90F6B9CCB3B5DFB79D60C851" type="personal">
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</mods:role>
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<mods:namePart id="0A40EAF16DF39E3B73BBCFC15CFA658C">Granica, Sebastian</mods:namePart>
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</mods:name>
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</mods:role>
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<mods:namePart id="BE1EE5B990DAEF960F7117F566AF8ADD">Vitalini, Sara</mods:namePart>
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</mods:name>
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<mods:name id="4B301D25566DB8726F779C5593B700B3" type="personal">
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</mods:role>
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<mods:namePart id="C68142470858C1C15FA039CA833655D7">Zidorn, Christian</mods:namePart>
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</mods:name>
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<mods:typeOfResource id="3A05C2D983970773A38A3AFDDC42AA57">text</mods:typeOfResource>
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<mods:title id="F467FAA3668F08101C8E62F794669A48">Phytochemistry</mods:title>
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<mods:part id="567DCE774FC9D5AFE5E419898CBF8B65">
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<mods:date id="B74B0B362E460DD81AD771AA4F7DCD6E">2015</mods:date>
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<mods:number id="A6CA98BCD2283413A1B77D3C20D24ED5">2015-07-31</mods:number>
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<mods:number id="71B557839021AE433904C562B1C95848">115</mods:number>
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<mods:detail id="C846B74EC38B61BD985E97D697D1EA21" type="issue">
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<mods:number id="2CF4BF4F8DF68195E3431BF5738A5E97">1</mods:number>
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<mods:start id="268723EF6A21C2831623A81A487C71CB">27</mods:start>
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<mods:end id="79D581B60BCEECFE595477431B0B28F3">43</mods:end>
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<mods:url id="468AFC5ABDC0497070A1FF80F4A4CCD6">http://dx.doi.org/10.1016/j.phytochem.2015.02.014</mods:url>
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</mods:location>
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<mods:classification id="FE06E5953350BE1DA2BE0C6317A065AA">journal article</mods:classification>
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<mods:identifier id="4A5C881F1FABF4EF156FB72FA3DD1F95" type="CLB-Dataset">285349</mods:identifier>
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<mods:identifier id="682C8D678B014E360F247050EC293EEB" type="DOI">10.1016/j.phytochem.2015.02.014</mods:identifier>
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<mods:identifier id="0E639EB0FDA3A525B0D1C6C62CE3975D" type="GBIF-Dataset">d30e1c4c-6a0f-4e42-97ec-8f9abb4e26ea</mods:identifier>
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<mods:identifier id="B8F6338C3B573A9F460B6118D6821BED" type="ISSN">1873-3700</mods:identifier>
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<mods:identifier id="B86A8E688FC45279035A3632F91DBD7B" type="Zenodo-Dep">10486867</mods:identifier>
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</mods:mods>
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<treatment id="03A0E701A375FFB5FCDA048EFA3740F4" LSID="urn:lsid:plazi:treatment:03A0E701A375FFB5FCDA048EFA3740F4" httpUri="http://treatment.plazi.org/id/03A0E701A375FFB5FCDA048EFA3740F4" lastPageNumber="35" pageId="8" pageNumber="35">
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<subSubSection id="C313059CA375FFB5FCDA048EFC4A4286" box="[831,958,1175,1195]" pageId="8" pageNumber="35" type="nomenclature">
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<paragraph id="8BB65617A375FFB5FCDA048EFC4A4286" blockId="8.[831,958,1175,1195]" box="[831,958,1175,1195]" pageId="8" pageNumber="35">
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<heading id="D0FEE17BA375FFB5FCDA048EFC4A4286" box="[831,958,1175,1195]" fontSize="36" level="2" pageId="8" pageNumber="35" reason="3">
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<emphasis id="B97D8A05A375FFB5FCDA048EFC4A4286" box="[831,958,1175,1195]" italics="true" pageId="8" pageNumber="35">
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3.8.
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<taxonomicName id="4C092D94A375FFB5FC8D048EFC4A4286" ID-CoL="6Z3XQ" authority="Nakai" authorityName="Nakai" box="[872,958,1175,1195]" class="Magnoliopsida" family="Rutaceae" genus="Skimmia" kingdom="Plantae" order="Sapindales" pageId="8" pageNumber="35" phylum="Tracheophyta" rank="species" species="repens">S. repens</taxonomicName>
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</emphasis>
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</heading>
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</paragraph>
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</subSubSection>
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<subSubSection id="C313059CA375FFB5FCBB04D6FA3740F4" pageId="8" pageNumber="35" type="discussion">
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<paragraph id="8BB65617A375FFB5FCBB04D6FA3740F4" blockId="8.[831,1501,1231,1753]" pageId="8" pageNumber="35">
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<taxonomicName id="4C092D94A375FFB5FCBB04D6FC4042CE" box="[862,948,1231,1251]" class="Magnoliopsida" family="Rutaceae" genus="Skimmia" kingdom="Plantae" order="Sapindales" pageId="8" pageNumber="35" phylum="Tracheophyta" rank="species" species="repens">
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<emphasis id="B97D8A05A375FFB5FCBB04D6FC4042CE" box="[862,948,1231,1251]" italics="true" pageId="8" pageNumber="35">S. repens</emphasis>
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</taxonomicName>
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is a shrub, native to the Himalyan region, often cultivated for decorative purposes. (
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<bibRefCitation id="EF982BE6A375FFB5FB9B04F5FA8E42D2" author="Ohta, T. & Miyazaki, T." box="[1150,1402,1260,1279]" pageId="8" pageNumber="35" pagination="463 - 464" refId="ref16821" refString="Ohta, T., Miyazaki, T., 1956. Yakugaku Zasshi 76, 463 - 464." type="journal article" year="1956">
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Ohta and
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<collectingRegion id="49CD98F5A375FFB5FB0404F5FACA42D2" box="[1249,1342,1260,1279]" country="Japan" name="Miyazaki" pageId="8" pageNumber="35">Miyazaki</collectingRegion>
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, 1956
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</bibRefCitation>
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) The first phytochemical study about
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<taxonomicName id="4C092D94A375FFB5FBB8051EFB404336" box="[1117,1204,1287,1307]" class="Magnoliopsida" family="Rutaceae" genus="Skimmia" kingdom="Plantae" order="Sapindales" pageId="8" pageNumber="35" phylum="Tracheophyta" rank="species" species="repens">
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<emphasis id="B97D8A05A375FFB5FBB8051EFB404336" box="[1117,1204,1287,1307]" italics="true" pageId="8" pageNumber="35">S. repens</emphasis>
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</taxonomicName>
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dates back to 1930 when in two distinct papers Asahina et al. 1930 reported the isolation of the alkaloids skimmianine
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<emphasis id="B97D8A05A375FFB5FBB70526FB9F437F" bold="true" box="[1106,1131,1343,1362]" pageId="8" pageNumber="35">13</emphasis>
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and dictamnine
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<emphasis id="B97D8A05A375FFB5FAFC0526FAC6437F" bold="true" box="[1305,1330,1343,1362]" pageId="8" pageNumber="35">12</emphasis>
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from extracts of the whole plant. The structure of the latter compound was unambiguously confirmed by chemical synthesis in 1956 and 1957 by Sato and Ohta who obtained dictamnine and its direct precursor dictamnal. In 1938
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<bibRefCitation id="EF982BE6A375FFB5FBE005B6FAE243EF" author="Spath, E. & Neufeld, O." box="[1029,1302,1455,1474]" pageId="8" pageNumber="35" pagination="353 - 356" refId="ref18221" refString="Spath, E., Neufeld, O., 1938 a. Natural coumarins XXXVI. Occurrence of seselin in Japanese Skimmia species. Chem. Ber. 71, 353 - 356." type="journal article" year="1938">Späth and Neufeld (1938a)</bibRefCitation>
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turned their attention to the coumarin profile of the ether extract of the title plant and described the isolation and structural determination of seselin
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<emphasis id="B97D8A05A375FFB5FCDA061AFCAC403B" bold="true" box="[831,856,1539,1558]" pageId="8" pageNumber="35">65</emphasis>
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. About twenty years later
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<bibRefCitation id="EF982BE6A375FFB5FB8F061AFA80403B" author="Ohta, T. & Miyazaki, T." box="[1130,1396,1539,1558]" pageId="8" pageNumber="35" pagination="463 - 464" refId="ref16821" refString="Ohta, T., Miyazaki, T., 1956. Yakugaku Zasshi 76, 463 - 464." type="journal article" year="1956">
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Ohta and
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<collectingRegion id="49CD98F5A375FFB5FB2B061AFADD403B" box="[1230,1321,1539,1558]" country="Japan" name="Miyazaki" pageId="8" pageNumber="35">Miyazaki</collectingRegion>
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(1956)
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</bibRefCitation>
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described the fatty acid profile of the apolar extract of fruits of
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<taxonomicName id="4C092D94A375FFB5FA660604FA28401C" box="[1411,1500,1565,1585]" class="Magnoliopsida" family="Rutaceae" genus="Skimmia" kingdom="Plantae" order="Sapindales" pageId="8" pageNumber="35" phylum="Tracheophyta" rank="species" species="repens">
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<emphasis id="B97D8A05A375FFB5FA660604FA28401C" box="[1411,1500,1565,1585]" italics="true" pageId="8" pageNumber="35">S. repens</emphasis>
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</taxonomicName>
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and found that palmitic and stearic acids were the main components with minor percentages of linolenic, linoleic, and oleic acids listed in increasing order.
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<taxonomicName id="4C092D94A375FFB5FBB10668FB5840A8" box="[1108,1196,1649,1669]" class="Magnoliopsida" family="Rutaceae" genus="Skimmia" kingdom="Plantae" order="Sapindales" pageId="8" pageNumber="35" phylum="Tracheophyta" rank="species" species="repens">
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<emphasis id="B97D8A05A375FFB5FBB10668FB5840A8" box="[1108,1196,1649,1669]" italics="true" pageId="8" pageNumber="35">S. repens</emphasis>
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</taxonomicName>
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so far yielded only few secondary metabolites and more detailed future investigations, both phytochemical and pharmacological, are destined to reveal new activities and additional secondary metabolites for this species.
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</paragraph>
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</subSubSection>
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</treatment>
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</document>
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