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110 lines
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<document id="3848D6F3C9BD473D441E84AE8C0D7327" ID-DOI="10.1016/j.phytochem.2018.05.008" ID-ISSN="1873-3700" ID-Zenodo-Dep="10483984" IM.bibliography_approvedBy="felipe" IM.illustrations_approvedBy="felipe" IM.materialsCitations_approvedBy="juliana" IM.metadata_approvedBy="juliana" IM.taxonomicNames_approvedBy="juliana" IM.treatments_approvedBy="juliana" checkinTime="1704938445945" checkinUser="felipe" docAuthor="Fiorito, Serena, Epifano, Francesco, Preziuso, Francesca, Taddeo, Vito Alessandro & Genovese, Salvatore" docDate="2018" docId="0385EF62FF91FF82FC91D672FC283287" docLanguage="en" docName="Phytochemistry.153.1-10.pdf" docOrigin="Phytochemistry 153" docSource="http://dx.doi.org/10.1016/j.phytochem.2018.05.008" docStyle="DocumentStyle:9E596C34F4E94307D29315B03ACE1007.6:Phytochemistry.2014-2019.journal_article" docStyleId="9E596C34F4E94307D29315B03ACE1007" docStyleName="Phytochemistry.2014-2019.journal_article" docStyleVersion="6" docTitle="Lilium spp" docType="treatment" docVersion="1" lastPageNumber="6" masterDocId="FFBC971AFF94FF87FFA3D759FFC03138" masterDocTitle="Selenylated plant polysaccharides: A survey of their chemical and pharmacological properties" masterLastPageNumber="10" masterPageNumber="1" pageNumber="6" updateTime="1705322845058" updateUser="juliana">
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<mods:title id="20C31880FC0BA0218A7969531B5FA156">Selenylated plant polysaccharides: A survey of their chemical and pharmacological properties</mods:title>
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<mods:namePart id="E050F7144DD11E2E41C8552B6FF98975">Fiorito, Serena</mods:namePart>
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<mods:affiliation id="273FA4003394050DE7138D2FB91C53A4">Dipartimento di Farmacia, Università “ G. d’Annunzio ” of Chieti-Pescara, Via dei Vestini 31, 66100, Chieti Scalo, CH, Italy & Dipartimento di Scienze Farmaceutiche, Università degli Studi di Perugia, Via del Liceo, 06123, Perugia, Italy</mods:affiliation>
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<mods:namePart id="98CDF94FDD424737E26F248E1F1F57B0">Epifano, Francesco</mods:namePart>
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<mods:affiliation id="346A5728E7811A3A9284A9AB04C435FB">Dipartimento di Farmacia, Università “ G. d’Annunzio ” of Chieti-Pescara, Via dei Vestini 31, 66100, Chieti Scalo, CH, Italy</mods:affiliation>
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<mods:nameIdentifier id="A17CAA63C13BA0E441D2116B6F0C7079" type="email">fepifano@unich.it</mods:nameIdentifier>
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<mods:namePart id="7BEA860434872CA34A551CAA87BD0355">Preziuso, Francesca</mods:namePart>
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<mods:affiliation id="23768169B3E5C2D0578B7E4CBD7B2B21">Dipartimento di Farmacia, Università “ G. d’Annunzio ” of Chieti-Pescara, Via dei Vestini 31, 66100, Chieti Scalo, CH, Italy</mods:affiliation>
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<mods:namePart id="B376145F041708192454F3F38626AEF3">Taddeo, Vito Alessandro</mods:namePart>
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<mods:affiliation id="D785A7FBD2B68E2709CEF2C9B5ED0D97">Dipartimento di Farmacia, Università “ G. d’Annunzio ” of Chieti-Pescara, Via dei Vestini 31, 66100, Chieti Scalo, CH, Italy</mods:affiliation>
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<mods:namePart id="FDB6BE1C6A27936BF77D730386984C89">Genovese, Salvatore</mods:namePart>
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<mods:affiliation id="BAF4E57F4E07A82F424D92A6DA2E9A04">Dipartimento di Farmacia, Università “ G. d’Annunzio ” of Chieti-Pescara, Via dei Vestini 31, 66100, Chieti Scalo, CH, Italy</mods:affiliation>
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<mods:title id="E806D130F940C74F30F5D708FBF4C134">Phytochemistry</mods:title>
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</mods:titleInfo>
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<mods:part id="4E7282007DF645BC3AE00CFC937B58DD">
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<mods:date id="69566523A727CAA4DBF868AC11592B9F">2018</mods:date>
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<mods:number id="7504210D98B74E991227DF66126AA526">2018-09-30</mods:number>
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<mods:number id="9BA46389363169F682EF02D1B0D78166">153</mods:number>
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<mods:start id="2D5A2D2942D1A6A8EBDE56B064C35643">1</mods:start>
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<mods:url id="AC16D96B6A5EA14F80B9ADF1E23A7544">http://dx.doi.org/10.1016/j.phytochem.2018.05.008</mods:url>
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<mods:classification id="27AF24E2ACE6FB2FFA673BAD62400401">journal article</mods:classification>
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<mods:identifier id="7137426F870947350FAE0535C025B93C" type="DOI">10.1016/j.phytochem.2018.05.008</mods:identifier>
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<mods:identifier id="B9B13D1B40188BE3C6124B7E2FF46B03" type="ISSN">1873-3700</mods:identifier>
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<mods:identifier id="2FF10224EBCFF16687C6B13F7BF4B00C" type="Zenodo-Dep">10483984</mods:identifier>
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</mods:mods>
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<treatment id="0385EF62FF91FF82FC91D672FC283287" LSID="urn:lsid:plazi:treatment:0385EF62FF91FF82FC91D672FC283287" httpUri="http://treatment.plazi.org/id/0385EF62FF91FF82FC91D672FC283287" lastPageNumber="6" pageId="5" pageNumber="6">
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<subSubSection id="C3360DFFFF91FF82FC91D672FC193006" box="[818,985,299,318]" pageId="5" pageNumber="6" type="nomenclature">
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<paragraph id="8B935E74FF91FF82FC91D672FC193006" blockId="5.[818,985,299,318]" box="[818,985,299,318]" pageId="5" pageNumber="6">
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<heading id="D0DBE918FF91FF82FC91D672FC193006" bold="true" box="[818,985,299,318]" fontSize="36" level="1" pageId="5" pageNumber="6" reason="1">
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<emphasis id="B9588266FF91FF82FC91D672FC193006" bold="true" box="[818,985,299,318]" italics="true" pageId="5" pageNumber="6">
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5.11.1.
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<taxonomicName id="4C2C25F7FF91FF82FCDED672FC193006" box="[893,985,299,318]" class="Liliopsida" family="Liliaceae" genus="Lilium" kingdom="Plantae" order="Liliales" pageId="5" pageNumber="6" phylum="Tracheophyta" rank="species" species="spp">Lilium spp</taxonomicName>
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</emphasis>
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</heading>
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</paragraph>
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</subSubSection>
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<subSubSection id="C3360DFFFF91FF82FCF0D61EFC283287" pageId="5" pageNumber="6" type="description">
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<paragraph id="8B935E74FF91FF82FCF0D61EFC283287" blockId="5.[818,1487,327,959]" pageId="5" pageNumber="6">
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The term “Lily” indicates a mixture of dry leaves of three species belonging to the
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<taxonomicName id="4C2C25F7FF91FF82FC75D63AFBE9304E" authorityName="de Jussieu" authorityYear="1789" box="[982,1065,355,374]" class="Liliopsida" family="Liliaceae" kingdom="Plantae" order="Liliales" pageId="5" pageNumber="6" phylum="Tracheophyta" rank="family">Liliaceae</taxonomicName>
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family:
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<taxonomicName id="4C2C25F7FF91FF82FBDAD63AFC3530AA" authority="Baker" authorityName="Baker" class="Liliopsida" family="Liliaceae" genus="Lilium" kingdom="Plantae" order="Liliales" pageId="5" pageNumber="6" phylum="Tracheophyta" rank="variety" species="lancifolium" subSpecies="brownii" variety="viridulum">
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<emphasis id="B9588266FF91FF82FBDAD63AFADC304E" bold="true" box="[1145,1308,355,374]" italics="true" pageId="5" pageNumber="6">Lilium lancifolium</emphasis>
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Thunb.,
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<emphasis id="B9588266FF91FF82FAD7D63AFA0F304E" bold="true" box="[1396,1487,355,374]" italics="true" pageId="5" pageNumber="6">L. brownii</emphasis>
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var.
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<emphasis id="B9588266FF91FF82FCFCD626FC7430AA" bold="true" box="[863,948,383,402]" italics="true" pageId="5" pageNumber="6">viridulum</emphasis>
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Baker
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</taxonomicName>
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, and
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<taxonomicName id="4C2C25F7FF91FF82FB8ED626FB1B30AA" authority="Delile." authorityName="Delile." box="[1069,1243,383,402]" class="Liliopsida" family="Liliaceae" genus="Lilium" kingdom="Plantae" order="Liliales" pageId="5" pageNumber="6" phylum="Tracheophyta" rank="species" species="pumilum">
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<emphasis id="B9588266FF91FF82FB8ED626FB5430AA" bold="true" box="[1069,1172,383,402]" italics="true" pageId="5" pageNumber="6">L. pumilum</emphasis>
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Delile.
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</taxonomicName>
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This phytopreparation is part of the Chinese herbal medicine tradition and used as an immunomodulatory, anti-cancer, and anti-diabetic remedy. In 2016 Hou and coworkers synthesized a library of 9 samples with Se content ranging from
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<quantity id="4CD4F391FF91FF82FCC4D6B7FC053339" box="[871,965,494,513]" metricMagnitude="-5" metricUnit="kg" metricValue="1.177" pageId="5" pageNumber="6" unit="mg" value="11.77">11.77 mg</quantity>
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/g to
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<quantity id="4CD4F391FF91FF82FC5FD6B7FB8E3339" box="[1020,1102,494,513]" metricMagnitude="-5" metricUnit="kg" metricValue="3.9799999999999995" pageId="5" pageNumber="6" unit="mg" value="39.8">39.8 mg</quantity>
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/g and yields from 22.6% to 41.3%. All samples were then assayed for their capacity to enhance the immune response recording the extent of chicken peripheral lymphocytes proliferation applying doses ranging from 0.391 μg/mL to 6.25 μg/mL. The observed increase of this parameter was however modest (+15%) although higher than the native polysaccharide. The best effect was shown by the Se-P with the highest content of Se and then the same was selected to perform
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<emphasis id="B9588266FF91FF82FC58D5E8FBFA33FC" bold="true" box="[1019,1082,689,708]" italics="true" pageId="5" pageNumber="6">in vivo</emphasis>
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studies using 14-days old White Roman chickens vaccinated with ND vaccine. The biochemical parameters measured were peripheral lymphocytes proliferation, serum antibody titer, and production of IL-2, IL-6, and IFN-γ. The dose applied was
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<quantity id="4CD4F391FF91FF82FC91D478FCA1320C" box="[818,865,801,820]" metricMagnitude="-6" metricUnit="kg" metricValue="2.0" pageId="5" pageNumber="6" unit="mg" value="2.0">2 mg</quantity>
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/kg administered i.m. for 3 days. Recordings were made every week along a period of 4 weeks. Se-P provided a marked increase of cell proliferation rate (40%–60%, 2-fold and about 4-fold respect to animals treated with the native polysaccharide and only with the vehicle). On the other hand virtually no differences were noted for the release of both ILs and IFN-γ.
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</paragraph>
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</subSubSection>
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</treatment>
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</document>
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