124 lines
6.2 KiB
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124 lines
6.2 KiB
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@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
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@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
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@prefix bibo: <http://purl.org/ontology/bibo/> .
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@prefix cito: <http://purl.org/spar/cito/> .
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@prefix dc: <http://purl.org/dc/elements/1.1/> .
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@prefix dwc: <http://rs.tdwg.org/dwc/terms/> .
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@prefix dwcFP: <http://filteredpush.org/ontologies/oa/dwcFP#> .
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@prefix fabio: <http://purl.org/spar/fabio/> .
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@prefix trt: <http://plazi.org/vocab/treatment#> .
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@prefix xlink: <http://www.w3.org/1999/xlink/> .
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<http://treatment.plazi.org/id/BB74B629FFE1FFCCE651FB9904586981>
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cito:cites <http://dx.doi.org/10.5281/zenodo.8293510>, <http://dx.doi.org/10.5281/zenodo.8293512>, <http://dx.doi.org/10.5281/zenodo.8293514>, <http://dx.doi.org/10.5281/zenodo.8293516>, <http://dx.doi.org/10.5281/zenodo.8293518>, <http://dx.doi.org/10.5281/zenodo.8293520> ;
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dc:creator "Zheng, Sheng; Zhu, Ning; Shi, Cheng; Zheng, Heng" ;
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dc:title "Ganoderma sinense J. D. Zhao, L. W. Hsu & X. Q. Zhang" ;
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trt:publishedIn <http://dx.doi.org/10.1016/j.phytochem.2020.112466> ;
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trt:treatsTaxonName <http://taxon-name.plazi.org/id/Fungi/Ganoderma_sinense> ;
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a trt:Treatment .
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<http://dx.doi.org/10.1016/j.phytochem.2020.112466>
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bibo:endPage "8" ;
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bibo:journal "Phytochemistry" ;
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bibo:pubDate "2020-11-30" ;
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bibo:series "112466" ;
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bibo:startPage "1" ;
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bibo:volume "179" ;
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dc:creator "Zheng, Sheng; Zhu, Ning; Shi, Cheng; Zheng, Heng" ;
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dc:date "2020" ;
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dc:title "Genomic data mining approaches for the discovery of anticancer peptides from Ganoderma sinense" ;
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fabio:hasPart <http://dx.doi.org/10.5281/zenodo.8293510>, <http://dx.doi.org/10.5281/zenodo.8293512>, <http://dx.doi.org/10.5281/zenodo.8293514>, <http://dx.doi.org/10.5281/zenodo.8293516>, <http://dx.doi.org/10.5281/zenodo.8293518>, <http://dx.doi.org/10.5281/zenodo.8293520> ;
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a fabio:JournalArticle .
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<http://taxon-name.plazi.org/id/Fungi/Ganoderma_sinense>
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dwc:class "Agaricomycetes" ;
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dwc:family "Ganodermataceae" ;
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dwc:genus "Ganoderma" ;
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dwc:kingdom "Fungi" ;
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dwc:order "Polyporales" ;
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dwc:phylum "Basidiomycota" ;
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dwc:rank "species" ;
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dwc:species "sinense" ;
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trt:hasParentName <http://taxon-name.plazi.org/id/Fungi/Ganoderma> ;
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a dwcFP:TaxonName .
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<http://taxon-name.plazi.org/id/Fungi/Ganoderma>
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dwc:class "Agaricomycetes" ;
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dwc:family "Ganodermataceae" ;
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dwc:genus "Ganoderma" ;
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dwc:kingdom "Fungi" ;
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dwc:order "Polyporales" ;
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dwc:phylum "Basidiomycota" ;
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dwc:rank "genus" ;
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trt:hasParentName <http://taxon-name.plazi.org/id/Fungi/Ganodermataceae> ;
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a dwcFP:TaxonName .
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<http://taxon-name.plazi.org/id/Fungi/Ganodermataceae>
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dwc:class "Agaricomycetes" ;
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dwc:family "Ganodermataceae" ;
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dwc:kingdom "Fungi" ;
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dwc:order "Polyporales" ;
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dwc:phylum "Basidiomycota" ;
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dwc:rank "family" ;
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trt:hasParentName <http://taxon-name.plazi.org/id/Fungi/Polyporales> ;
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a dwcFP:TaxonName .
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<http://taxon-name.plazi.org/id/Fungi/Polyporales>
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dwc:class "Agaricomycetes" ;
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dwc:kingdom "Fungi" ;
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dwc:order "Polyporales" ;
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dwc:phylum "Basidiomycota" ;
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dwc:rank "order" ;
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trt:hasParentName <http://taxon-name.plazi.org/id/Fungi/Agaricomycetes> ;
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a dwcFP:TaxonName .
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<http://taxon-name.plazi.org/id/Fungi/Agaricomycetes>
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dwc:class "Agaricomycetes" ;
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dwc:kingdom "Fungi" ;
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dwc:phylum "Basidiomycota" ;
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dwc:rank "class" ;
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trt:hasParentName <http://taxon-name.plazi.org/id/Fungi/Basidiomycota> ;
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a dwcFP:TaxonName .
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<http://taxon-name.plazi.org/id/Fungi/Basidiomycota>
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dwc:kingdom "Fungi" ;
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dwc:phylum "Basidiomycota" ;
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dwc:rank "phylum" ;
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trt:hasParentName <http://taxon-name.plazi.org/id/Fungi> ;
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a dwcFP:TaxonName .
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<http://taxon-name.plazi.org/id/Fungi>
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dwc:kingdom "Fungi" ;
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dwc:rank "kingdom" ;
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a dwcFP:TaxonName .
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<http://dx.doi.org/10.5281/zenodo.8293510>
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dc:description "Fig. 1. Protein length distribution in the G. sinense proteome." ;
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fabio:hasRepresentation <https://zenodo.org/record/8293510/files/figure.png> ;
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a fabio:Figure .
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<http://dx.doi.org/10.5281/zenodo.8293512>
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dc:description "Fig. 2. Experimental flowchart. (A) Blast search and alignment of G. sinense proteins with known anticancer peptides. (B) An example of a Hit sequence. (C) Hit sequences were cleaved by in silico enzyme digestion of trypsin. (D) The digested fragments were screened by mACPpred, an SVM-based algorithm, to identify putative ACPs. (E) The resulting peptides were then subjected to sequence comparison to known ACPs." ;
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fabio:hasRepresentation <https://zenodo.org/record/8293512/files/figure.png> ;
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a fabio:Figure .
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<http://dx.doi.org/10.5281/zenodo.8293514>
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dc:description "Fig. 3. The number of parent proteins containing putative ACPs." ;
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fabio:hasRepresentation <https://zenodo.org/record/8293514/files/figure.png> ;
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a fabio:Figure .
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<http://dx.doi.org/10.5281/zenodo.8293516>
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dc:description "Fig. 4. Length distributions of cleaved peptides. The parent proteins were cleaved by in silico enzyme digestion with trypsin. The length distributions of peptides between 7 and 19 amino acids in length are shown." ;
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fabio:hasRepresentation <https://zenodo.org/record/8293516/files/figure.png> ;
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a fabio:Figure .
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<http://dx.doi.org/10.5281/zenodo.8293518>
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dc:description "Fig. 5. Energy change in 100-ns molecular dynamic simulation of putative ACPs P14 and P15 (trypsin-digested fragments from parent proteins No. 14 and 15 in the G. sinense proteome). Molecular dynamic simulation was performed by AMBER14." ;
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fabio:hasRepresentation <https://zenodo.org/record/8293518/files/figure.png> ;
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a fabio:Figure .
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<http://dx.doi.org/10.5281/zenodo.8293520>
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dc:description "Fig. 6. Three-dimensional structures of P14 and P15, shown in cartoon representation; red represents α-helix, yellow represents β-sheet, and blue represents turn structure. Structures were extracted from the trajectory of molecular dynamic simulation from 20 ns to 100 ns. The lowest energy conformation is presented. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)" ;
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fabio:hasRepresentation <https://zenodo.org/record/8293520/files/figure.png> ;
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a fabio:Figure .
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