@prefix rdf: . @prefix rdfs: . @prefix bibo: . @prefix cito: . @prefix dc: . @prefix dwc: . @prefix dwcFP: . @prefix fabio: . @prefix trt: . cito:cites , , , ; dc:creator "Lu, Xiaoxiao; Xie, Chunqin; Wang, Yunxiao; Liu, Yongnan; Han, Jing; Shi, Liang; Zhu, Jing; Yu, Hanshou; Ren, Ang; Zhao, Mingwen" ; dc:title "Ganoderma lucidum subsp. contains P. Karst." ; trt:augmentsTaxonConcept ; trt:publishedIn ; a trt:Treatment . bibo:endPage "9" ; bibo:journal "Phytochemistry" ; bibo:pubDate "2020-04-30" ; bibo:series "112283" ; bibo:startPage "1" ; bibo:volume "172" ; dc:creator "Lu, Xiaoxiao; Xie, Chunqin; Wang, Yunxiao; Liu, Yongnan; Han, Jing; Shi, Liang; Zhu, Jing; Yu, Hanshou; Ren, Ang; Zhao, Mingwen" ; dc:date "2020" ; dc:title "Function of ceramide synthases on growth, ganoderic acid biosynthesis and sphingolipid homeostasis in Ganoderma lucidum" ; fabio:hasPart , , , ; a fabio:JournalArticle . dwc:ID-ENA "5315" ; dwc:authority "(Curtis) P. Karst." ; dwc:authorityName "P. Karst." ; dwc:baseAuthorityName "Curtis" ; dwc:class "Agaricomycetes" ; dwc:family "Ganodermataceae" ; dwc:genus "Ganoderma" ; dwc:kingdom "Fungi" ; dwc:order "Polyporales" ; dwc:phylum "Basidiomycota" ; dwc:rank "species" ; dwc:scientificNameAuthorship "(Curtis) Karst." ; dwc:species "lucidum" ; rdfs:seeAlso ; trt:hasTaxonName ; a dwcFP:TaxonConcept . dwc:class "Agaricomycetes" ; dwc:family "Ganodermataceae" ; dwc:genus "Ganoderma" ; dwc:kingdom "Fungi" ; dwc:order "Polyporales" ; dwc:phylum "Basidiomycota" ; dwc:rank "species" ; dwc:species "lucidum" ; trt:hasParentName ; a dwcFP:TaxonName . dwc:genus "Ganoderma" ; dwc:rank "genus" ; trt:hasParentName ; a dwcFP:TaxonName . dwc:family "Ganodermataceae" ; dwc:rank "family" ; trt:hasParentName ; a dwcFP:TaxonName . dwc:order "Polyporales" ; dwc:rank "order" ; trt:hasParentName ; a dwcFP:TaxonName . dwc:class "Agaricomycetes" ; dwc:rank "class" ; trt:hasParentName ; a dwcFP:TaxonName . dwc:phylum "Basidiomycota" ; dwc:rank "phylum" ; trt:hasParentName ; a dwcFP:TaxonName . dwc:kingdom "Fungi" ; dwc:rank "kingdom" ; a dwcFP:TaxonName . dc:description "Fig. 2. G. lucidum harbours three ceramide synthases. Phylogenetic analysis of ceramide synthases in eukaryotes. The phylogenetic tree was conducted using MEGA 6 and can be roughly divided into three major groups: human, plant and fungi. The evolutionary history was inferred by the neighbour-joining method from 1000 replicates using MEGA 6." ; fabio:hasRepresentation ; a fabio:Figure . dc:description "Fig. 1. Overview of the sphingolipid biosynthetic pathway in yeast and filamentous fungi. The abbreviations used are as follows: Dihydroxy LCB: dihydroxy longchain (sphingoid) base; Trihydroxy LCB: trihydroxy long-chain sphingoid base; Long chain FA-CoA: long chain fatty acyl-coenzyme A; Very long chain FA-CoA: very long chain fatty acyl-coenzyme A; IPC synthase: inositol phosphorylceramide synthase; IPC mannosyl transferase: inositol phosphorylceramide mannosyl transferase; MIPCs: mannose inositol phosphorylceramides; M (IP)2Cs: mannose (inositol phosphoryl)2- ceramides." ; fabio:hasRepresentation ; a fabio:Figure . dc:description "Fig. 3. Effect of lag gene silencing on G. lucidum growth. Morphology of fungal colonies in lag-silenced, WT and SiControl strains after cultivation in the dark on CYM medium at 28 ̊C for 5 days. Three independent biological replicates in each column. Error bars represent standard deviations, and asterisks show significant differences from control (WT and Sicontrol) strains according to Student's t-test (**P <0.01, n = 3)." ; fabio:hasRepresentation ; a fabio:Figure . dc:description "Fig. 4. Ganoderic acid biosynthesis in G. lucidum is influenced by the lag gene. A Systematic content analysis of ganoderic acid in the lag-silenced, WT and SiControl strains. B–D Relative gene expression of hmgr (B), sqs (C) and osc (D) in the WT, SiControl and lag-silenced strains. There are three independent biological replicates in each column. Error bars represent standard deviations, and asterisks show significant differences from control (WT and Sicontrol) strains according to Student's t-test (**P <0.01, n = 3)." ; fabio:hasRepresentation ; a fabio:Figure .